Studies Enabled

The ACP Repository was developed to provide a much needed resource to the research community—high-quality samples and associated data from study participants with MS and selected other demyelinating diseases, and their affected and unaffected relatives and unrelated matched controls.

Since the launch of the repository, we have approved 112 requests for samples and data, 74 of which have come from academic/nonprofit institutions and the other 38 from industry research groups. Samples and data are available to researchers studying the causes of MS and related diseases.


Organizations using the ACP Repository for their research
  • 23andMe
  • Montreal Neurological Institute
  • St. Vincent's Hospital
  • Athabasca University
  • MSDx , LLC
  • Stanford
  • Beth Israel Deaconess Medical Center
  • NASA
  • SUNY Upstate Medical University
  • Biodesix
  • Ohio State University
  • SUNY Upstate Medical University
  • Biogen Idec
  • Oklahoma Medical Research Foundation
  • University of California Irvine
  • Brigham & Women’s Hospital
  • Pfizer
  • University of California San Francisco
  • DioGenix
  • Protagen AG
  • University of Maryland
  • Genelogic
  • Questcor
  • University of Michigan
  • GeNeuro SA
  • Regeneron
  • University of Texas Southwestern
  • Glycominds Ltd.
  • Science Commons
  • Vaccinex
  • Harvard School of Public Health
  • Scripps Research Institute
  • Vanderbilt
  • Johns Hopkins University
  • SomaLogic
  • Wellcome Trust Project
  • Knowledge Visualization Systems
  • Spectrum Health
  • Mayo Clinic
  • St. George's University of London


  • St. John's University


Examples of disorders studied
  • Multiple Sclerosis (MS)
  • Acute Disseminated Encephalomyelitis (ADEM)
  • Neuromyelitis Optica (NMO)
  • Clinically Isolated Syndrome (CIS)
  • Relapsing Remitting MS (RRMS)
  • Optic Neuritis (ON)
  • Secondary Progressive MS (SPMS)
  • Transverse Myelitis (TM)
  • Primary Progressive MS (PPMS)


Key topics of study
  • Data visualization
  • Immunology
  • Treatments and Therapeutics
  • Diagnostics
  • Risk Factors
  • Genetics



Study Focus: cell, tissue, pathway, or biological target
ApoA1 Klotho PrP
AQP-4 LiLr,Nogo
Semaphorin 4D
Blood brain barrier Microbiome


EBNA-1 Mycobacterium avium TH17
Epstein-Barr virus Myelin basic protein Toll-like receptor
Exome Metabolome NMO-IgG Transcriptome
Genome Non coding RNA including microRNA Tryptophan metabolism
Glycosylation pathway Pannexin-1 Visfatin
IL-6 pNF-H  
Kir 4.1 potassium channel Proteome