Delayed allergy to Tysabri seen
Submitted by art on Wed, 2007-10-31 05:55.
Although most hypersensitive reactions to Tysabri (natalizumab) occur within hours of the first dose, such responses may be delayed. Eight hours after one patient's second infusion of natalizumab he collapsed, developed a fever, arthralgias, urticarial exanthema, and a swollen lower lip. He recovered after treatment and was switched to another therapy.