Tovaxin Trial Fully Enrolled
Submitted by art on Wed, 2007-05-30 05:42.
Opexa Therapeutics announced the completion of patient enrollment in a 150-patient Phase IIb safety and efficacy study. This study will include 150 patients in a multicenter, randomized, double blind, placebo-controlled trial designed primarily to evaluate the efficacy, safety and tolerability of the Tovaxin T Cell vaccination with clinically isolated syndrome (CIS) and relapsing-remitting MS (RR-MS) patients. A total of 100 patients will receive Tovaxin, while 50 will receive placebo. The study is designed as a two-arm, 52-week, parallel-group study, whereby patients will be given five subcutaneous injections at 0, 4, 8, 12 and 24 weeks.
Tovaxin is interesting as it is a vaccination developed from the recipient's own cells.
M.S. Vaccine
Now this vaccine has proven safe and effective I would pay the company to access this for myself before the double blind trial outcomes are finalized.
I have been following this line of research for several years but it has proved elusive (appearing then vanishing just as rapidly for months even years at a time). I recently resorted to sending emails to the OHSU researchers involved over the years in the TCR vaccine research.
I have Secondary Progressive M.S. (22 years duration) and I'm feeling increasingly desperate to do something before my brain turns to mush. I recently paid the c. $20,000 to travel to Germany for adult stem cell treatment using my bone marrow in Sept 2006 but it's too early to tell if it is working yet.
The vaccine is next on my list, but I cannot afford to wait while they do their further research etc. after which we wait several years to get it in Australia. I must do something now and am even now considered 'too far gone (my words)' to be eligible for government subsidized meds.
I refuse to write myself off just yet even if the bean counters have.
Cathy Manners
Cathy - Have you tried
Cathy - Have you tried Tysabri? As long as you have had any "relapses", you can get it here in the United States.
Tovaxin
I am in complete agreement in with the first comment 100%. There always seem to be something difficult in finding out/accessing any relavant information regarding significant MS findings/studies. I firmly believe it's about money in large part and accountability of the "testers".
Find the cause find the Cure.
spiff PPMS