EAE labeled "misleading model of MS"
Submitted by art on Mon, 2005-12-12 08:04.
The medical journal "Annals of Neurology" recently published a review critical of the reliance on the mouse model EAE ( experimental allergic encephalomyelitis) in understanding and treating MS. The authors propose that the use of EAE be reconsidered, especially in the realm of therapy development. It will be interesting to see what reactions this critique provokes -- there are a lot of people working with EAE out there!
EAE is a disease that is induced in mice that is used to study MS. When you read a newspaper account that says 'mice with MS,' this is what they are talking about. Mice do not actually get MS.


Peter Behan and A Chaduri and EAE problems
eae
Re:eae