Low Dose Naltrexone (LDN)

I have spoken with numerous patients and followed them over time. LDN works..no doubt about it. If the US drug companies will not work on turning LDN into a blockbuster drug..the Europeans will do it for them. The genie is out of the bottle..

I've been on LDN a year. It has helped with fatigue & spasticity. Most days are highly functional unlike a year ago. It isn't a "miracle cure." I still have MS symptoms and right now they are increasing with the summer heat ... Even on LDN direct sunlight and temps over 80 degrees will bring on the symptoms of a drunken sailor. LDN side effects- increased insomnia but a deeper sleep cycle (I use melatonin to induce sleep) and burning sensation in stomach (I take with food/soy milk and calcium/vitamin D supplement). As to validity of this information ... Anecdotal data is all you may ever get. The chances of LDN going to a clinical trial are slim. Why??? It isn't profitable for the drug companies!!! My prescription costs less than my insurance co-pay. Unlike steroids and the ABCs, LDN doesn't shut down the immune system. If LDN does go to clinical trial for use in MS (it's already FDA approved in 10xhigher doses to help keep opiate addicts/alcoholics sober), it won't be in the U.S. Look to Europe to take the initiative!!! There's already been a 2-week trial in Germany and a handful of others are proposed.

of polls like this? as someone else said, it is totally unscientific. Is it just to make people who use LDN feel good about it?

I like the poll as we are getting the actaul first hand information from the patients perspective. We are waiting for scientific data which is often poorly done and trying to prove a particular agenda- that's why Boston Cure is so valuable -the agenda is not driven by an ego or a drug company's profit. I would like to see a poll on what foods and treatments have been found to be helpful. I personally am seeing a Chinese acupunturist and I am sure of the benefit-although I don't understand why it works and I am certain it also is dependant on the skill of the practioner. This person was recommended by people that I respected, word of mouth.

I started taking LDN on 7/08/03. From the first day I had increased leg strength and balance. Also significant improvement with urinary urgency and frequency. No further improvements but those mentioned have remained constant and no further progression.

I have taken LDN since Dec.17/2003. When I started LDN I was looking for wheelchair info. I was already using a walker. Now I can walk without assistance but need a cane at night.

At first I had trouble getting a prescription but then I called some compound pharmacys and asked them to tell me the names and phone numbers of Drs that had sent them prescriptions for LDN. I got the phone numbers, called the Dr. and made an appointment. I have PPMS and have been taking LDN for 30 days. So far it is not a miracle drug but I am sleeping well and am less fatigued during the day. That is worth $25.00 a month to me!