Flavonoid Luteolin suppresses EAE

Research in the Journal of Experimental Medicine reports that a flavonoid, luteolin, "substantially suppressed clinical symptoms and prevented relapse when administered either before or after disease onset" when tested on rats with EAE. Flavonoids are compounds occurring naturally in food, which are anti-oxidants and have anti-inflammatory properties.

A search for other work by the primary researcher of the above work found this article which provides a bit more detail on how the luteolin functions--by inhibiting nitric oxide production by macrophages.

This appears in line with other research showing that inosine supplementation raises uric acid levels; the uric acid acts as a scavenger of nitric oxide. In both cases, preventing production of or "mopping up" nitric oxide appears to be the protective mechanism.