Rethinking the primary problem in MS
With the recent studies showing iron deposits in MS brains, it seems to me that we should be re-thinking what the primary problem in MS is. Currently, we think of MS as an autoimmune disorder, and consequently the majority of research is focused on that. Should we not, instead, start thinking of MS primarily as a disorder of the BBB (Blood Brain Barrier)? Damage to the brian and CNS by iron and the body's own (killer) immune cells are a secondary consequence of the BBB breakdown. If the BBB functioned properly and these agents were not able to enter the brain/CNS, myelin destruction seen in MS would not be an issue, correct? So why are we all so focused on the autoimmune problem? Is that not secondary to the BBB problem? Sure, there is some research being done on the BBB problem (hence things like Antegren), but it's such a a small fraction.


BBB is where we should Be
Re:BBB is where we should Be