July 31, 2008

And it all seemed to be going so well. Biogen Idec just reported two confirmed cases of a deadly brain infection progressive multifocal leukoencephalopathy (PML) in patients taking the multiple sclerosis drug Tysabri. Both are in Europe and one patient is stable and at home, the other is still hospitalized.

They won't be pulling the drug, as this is a known complication, but it will certainly cause many to reconsider staying on it or getting on it. No details given around the circumstances particular to these individuals, but I'm sure they'll be forthcoming when they have them sorted out.

This study looking at white matter fiber tracts in the brains of people with MS has found that the atrophy of these tracts seems to be independent of lesions, implying a more diffuse process at work. Yet more evidence that MS is not a focal disease and that our measures of treatment efficacy surrounding lesion activity may not be the best.

Multiple Sclerosis Foundation's annual cruise is an innovative educational program at sea, "It's all about MEE" - Motivating, Educating and Empowering individuals with Multiple Sclerosis.

The MSF Cruise for a Cause is not a fundraising event - it is an innovative educational program at sea, providing the opportunity for people with MS to meet and learn from renowned MS specialists, hear motivational speakers, have fun with others with MS, and break beyond barriers - both physical and emotional - all aboard a luxury cruise ship.