Studies Enabled

Studies Enabled

The ACP Repository was developed to provide a much needed resource to the research community—high-quality samples and associated data from study participants with MS and selected other demyelinating diseases, and their affected and unaffected relatives and unrelated matched controls.

Since the launch of the repository, we have approved 63 requests for samples and data, 40 of which have come from academic/nonprofit institutions and the other 23 from industry research groups. Samples and data are available to researchers studying the causes of MS and related diseases.

Organizations using the ACP Repository for their research

  • 23andMe
  • Athabasca University
  • Beth Israel Deaconess Medical Center
  • Biodesix
  • Biogen Idec
  • Brigham & Women’s Hospital
  • DioGenix
  • Genelogic
  • GeNeuro SA
  • Glycominds Ltd.
  • Harvard School of Public Health
  • Johns Hopkins University
  • Knowledge Visualization Systems
  • Mayo Clinic
  • Montreal Neurological Institute
  • MSDx , LLC
  • NASA
  • Ohio State University
  • Oklahoma Medical Research Foundation
  • Pfizer
  • Protagen AG
  • Questcor
  • Regeneron
  • Science Commons
  • Scripps Research Institute
  • SomaLogic
  • Spectrum Health
  • St. George's University of London
  • St. John's University
  • St. Vincent's Hospital
  • Stanford
  • SUNY Upstate Medical University
  • University of California Irvine
  • University of California San Francisco
  • University of Maryland
  • University of Michigan
  • University of Texas Southwestern
  • Vaccinex
  • Vanderbilt
  • Wellcome Trust Project 

Examples of disorders studied

  • Multiple Sclerosis (MS)
  • Neuromyelitis Optica (NMO)
  • Relapsing Remitting MS (RRMS)
  • Secondary Progressive MS (SPMS)
  • Primary Progressive MS (PPMS)
  • Acute Disseminated Encephalomyelitis (ADEM)
  • Clinically Isolated Syndrome (CIS)
  • Optic Neuritis (ON)
  • Transverse Myelitis (TM)

Key topics of study

  • Data visualization
  • Diagnostics
  • Genetics
  • Immunology
  • Risk Factors
  • Treatments and Therapeutics

Key biological targets, genes, etc.

  • AQP-4
  • Blood brain barrier
  • CD24
  • Epstein-Barr virus
  • EBNA-1
  • Glycosylation pathway
  • MSRV
  • NMO-IgG
  • Mycobacterium avium
  • Myelin basic protein
  • pNF-H
  • PrP
  • SHP-1
  • Visfatin

Review our spreadsheet of ACP-Supported Research Projects to learn more the studies and to sort by topic, disease, biological targets, location, primary investigator, status, and more. Examples of scientific publications resulting from this research are also available for review.